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The Science

Passion Flower Extract

Paszkowski and Skrzypulec-Plinta,VAssessment of quality of life in women using Femelis Meno. Menopause Review. 2018 Jun 17 (2): 77-85

Goldstein SR, Mischoulon, D Poster Presented at: The 2015 North American Menopause Society Annual Meeting, September 30-October 3,2015; Las Vegas, NV, USA

Hellstron, AC, Muntzing, J, The Pollen Extract Femal-a Nonestrogenic Alternative to Hormone Therapy in Women with Menopausal Symptoms. Menopause:The Journal of the North American Menopause Society 2012 July Vol 19 (7) 825-829

Winther K, Rein E, Hedman C. Femal, A herbal remedy made from pollen extracts, reduces hot flushes and improves quality of life in menopausal women: a randomized, placebo-controlled, parallel study. Climacteric. 2005;8:162-170.

Ngan, A, Coduit, R. A double-blind, placebo-controlled investigation of the effects of Passiflora incarnata (passionflower) herbal tea on subjective sleep quality. Phytother Res 2011 Aug;25(8):11539.doi:10.1002/ptr.3400. Epub 2011 Feb 3

Pine Bark Extract, L Arginine, L Citrulline, Rose Hip Extract

Stanislavov R, Rohdewald P. PACR (Pine Bark Extract, L Arginine, L Citrulline, Rose Hip Extract) Improves Emotional, Physical Health and Sexual Function in Peri-Menopausal Women. J Women’s Health Care. 2014;3:6.

Winther K, Hedman C. Assessment of the Effects of the Herbal Remedy Femal on the Symptoms of Premenstrual Syndrome: A Randomized, Double-Blind,Placebo-Controlled Study. Curr Ther Res Clin Exp. 2002;63(5):344-353.

Pine Bark Extract

Kohama T, Negami M. Effect of low-dose French maritime pine bark extract on climacteric syndrome in 170 perimenopausal women: a randomized, double-blind, placebo-controlled trial. J Reprod Med. 2013 Jan-Feb;58(1-2):39-46.

Errichi S, Bottari A, Belcaro G, Cesarone M, Hosoi M, et al. Supplementation with Pycnogenol® improves signs and symptoms of menopausal transition. Panminerva Medica 53: 65-70. 21

Rohdewald, P., A review of the French maritime pine bark extract (Pycnogenol), a herbal medication with a diverse clinical pharmacology. Int J Clin Pharmacol Ther. 2002 Apr;40(4):158-68.

Stanislavov R, Nikolova V.Treatment of erectile dysfunction with pycnogenol and L-arginine. J Sex Marital Ther. 2003 May-Jun;29(3):207-13.


Chandrasekhar, K,, Kapoor, J, Anishetty, SA Prospective, Randomized Double-Blind, Placebo-Controlled Study of Safety and Efficacy of a High-Concentration Full-Spectrum Extract of Ashwagandha Root in Reducing Stress and Anxiety in Adults. Indian J Psychol Med. 2012 Jul-Sep; 34(3): 255–262.

Afr J Tradit Complement Altern Med. 2011; 8(5 Suppl): 208–213.
Published online 2011 Jul 3. doi: 10.4314/ajtcam.v8i5S.9


Ritsner S, Michael, MD, Miodownik, Chanoch, MD, Ratner, Yael, MD, Shleifer, Tatyana, MD, Mar, Maria, MD, Pintov, Leonid, MD, Lerner, Vladimir, MD. L-Theanine Relieves Positive, Activation, and Anxiety Symptoms in Patients with Schizophrenia and Schizoaffective Disorder: An 8-Week, Randomized, Double-Blind, Placebo-Controlled, 2-Center Study. J Clin Psychiatry 2011

Higashiyama, A, Htay, HH, Ozeki, M, Juneja LR. Effects of L-Theanine on attention and reaction time response. Journal of Functional Foods 2011 July Vol 3 (3) 171-178

Lu, Kristy, Gray, Marcus, Oliver, Chris, Liley, David, Harrison, Ben, Bartholomeusz, Cali, Phan, K Luan. The Acute Effects of L-Theanine in Comparison with Alprazolam on Anticipatory Anxiety in Humans. Human Psychopharmacology: Clinical and Experiemntal 2004 July 26 doi.org/10.1002/hup.611

Kardashev A, Ratner, Y, Ritsner, M. Add-On Pregnenolone with L-Theanine to Antipsychotic Therapy Relieves Negative and Anxiety Symptoms of Schizophrenia: An 8-Week, Randomized, Double-Blind, Placebo-Controlled Trial. Clin Schizophr Relat Psychoses. Spring 2018;12(1):31-41. doi: 10.3371/CSRP.KARA.070415. Epub 2015 Jul 28

Chromium Picolinate

Anton, SD, Morrison, CS, Cefalu, WT, Effects of Chromium Picolinate on Food Intake and Satiety, Diabetes Technology 2008 10(5): 8167-8175

Wang, H, Kruszewski, A, Brautigan, D, Cellular Chromium Enhances Activation of Insulin Receptor Kinase† Biochemistry 2005, 44, 22, 8167-8175


Shaw, S, Wyatt, K, Campbell, J, Ernst, E, and Thompson‐Coon, J Vitex agnus castus for premenstrual syndrome Cochrane Database Syst Rev. 2018 Mar; 2018(3): CD004632.

Rafieian-Kopaei,M and Movahedi, M Systematic Review of Premenstrual, Postmenstrual and Infertility Disorders of Vitex Agnus Castus. Electron Physician. 2017 Jan; 9(1): 3685–3689.2017 Jan 25. doi: 10.19082/3685

Verkaik S, Kamperman A, Van Westrhenen R, and Schulte P. The treatment of premenstrual syndrome with preparations of Vitex agnus castus: A systematic review and meta-analysis. Am J Obstet Gynecol. 2017;217(2):150-166

Mirghafourvand M, Mohammad-Alizadeh-Charandabi S, Ahmadpour P, and Javadzadeh Y. Effects of Vitex agnus and Flaxseed on cyclic mastalgia: A randomized controlled trial. Complement Ther Med. 2016;24:90-95

Godfrey A and Saunders P. Principles and Practices of Naturopathic Botanical Medicine—Volume 1: Botanical Medicine Monographs. Toronto, ON: CCNM Press Inc; 2010.

Loch EG, Selle H, Boblitz N. Treatment of premenstrual syndrome with a phytopharmaceutical formulation containing Vitex agnus castus. J Womens Health Gend.Based.Med 2000;9:315-20

Schellenberg R. Treatment for the premenstrual syndrome with agnus castus fruit extract: prospective, randomised, placebo controlled study. BMJ 2001;20;322:134–7

Bohnert KJ, Hahn G. Clinical study on chaste tree for menstrual disorders. Quarterly Review of Natural Medicine 1997;Spring:19-21.

Royal Jelly

Taavoni, S, Barkhordari, F, Goushegir, A, Haghani, H. Effect of Royal Jelly on premenstrual syndrome among Iranian medical sciences students: A randomized, triple-blind, placebo-controlled study. Complementary Therapies in Medicine Volume 22, Issue 4, August 2014, Pages 601-606

Yakoot, M, Salem, A, Omar, A, Effectiveness of a Herbal Formula in Women with Menopausal Syndrome Forsch Komplementmed 2011;18:264–268


Beer, C, Wood, S, Veghte, R, A Clinical Trial to Investigate the Effect of Cynatine HNS on Hair and Nail Parameters. ScientificWorld Journal. 2014; 2014: 641723.

Beer C, Wood S, Veghte RHA randomized, double-blind, placebo-controlled clinical trial to investigate the effect of Cynatine(®) HNS on skin characteristics. Int J Cosmet Sci. 2013 Dec;35(6):608-12. doi: 10.1111/ics.12084. Epub 2013 Sep 2.

Proksch E, Segger D, Degwert J, Schunck M, Zague V, Oesser S.Oral supplementation of specific collagen peptides has beneficial effects on human skin physiology: a double-blind, placebo-controlled study. Skin Pharmacol Physiol. 2014;27(1):47-55. doi: 10.1159/000351376. Epub 2013 Aug 14.


Rao, A, et al. 2015 “Influence of LIBIFEM, a specialized extract of Trigonella foenum graecum (fenugreek) on sexual function, hormones and metabolism in healthy menstruating women, in a randomized placebo-controlled study.” Phytother. Res. DOI: 10.1002/ptr.5355.

Ginkgo Biloba

Lee, H., Birks, J., Ginkgo biloba for cognitive improvement in healthy individuals. Cochrane Database Syst Rev. 2018 Aug; 2018(8):

Effects of Ginkgo biloba in dementia: systematic review and meta-analysis.
Weinmann S, Roll S, Schwarzbach C, Vauth C, Willich SN.
BMC Geriatr. 2010 Mar 17;10:14. doi: 10.1186/1471-2318-10-14.


Before We Can Find Your Hormonal Cycle…

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How Old Are You?

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Since symptoms of hormonal cycles overlap, you may see a couple supplement choices.

If taking hormonal birth control, it’s impossible to know what hormonal cycle you are in. Consult with your health care provider or have a Hormonal Consult with Dr. Sherry

Ask Dr. Sherry

Still unsure?

Ask Dr. Sherry